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E450·raising agent

Diphosphates (Pyrophosphates)

Limit

Safety Assessment

BodyAcceptable Daily Intake (ADI)Year
JECFA0–70 mg/kg body weight/day (as phosphorus (group ADI with all phosphates)) · JECFA 1982(Expressed as as phosphorus (group ADI with all phosphates).)1982
EFSA

ADI = the amount of a substance a person can consume every day over a lifetime without appreciable health risk. Expressed as mg per kg body weight per day. Source: WHO/FAO JECFA Combined Compendium; EFSA OpenFoodTox 3.0.

Regulatory Status

JurisdictionStatusNotes
United StatesGRAS with usage limits
European UnionApproved with strict usage limits (revised phosphate ADI 2019)
JapanApproved with usage limits
South KoreaApproved (MFDS)
GBFSA approved with usage limits
VNApproved with usage limits
THApproved with usage limits
INFSSAI approved with category limits
AEApproved (GCC/GSO standards)
CNApproved per GB 2760

Scientific Notes

High cumulative phosphate intake (from all food sources) linked to cardiovascular and renal burden.

Primary Sources

Products on Looksee containing Diphosphates (Pyrophosphates)

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