Polyphosphates
Overview
Polyphosphates are inorganic phosphate compounds in which multiple phosphate units are linked in a chain — including sodium, potassium, and calcium polyphosphate salts. They function as moisture-retaining sequestrants, emulsifying salts, and acidity regulators in processed meats, fish products, processed cheese, and canned seafood. By binding to muscle proteins, they improve water-holding capacity, reduce cooking loss, and help maintain a tender texture in cooked and cured meat products.
JECFA's ADI for polyphosphates is 70 mg per kilogram body weight per day as phosphorus, evaluated in 1982, shared with all food phosphates (E338 through E342, E450). Polyphosphates are hydrolysed in the gut to orthophosphate before absorption. This group ADI was set out of precautionary concern about cumulative phosphate intake rather than specific polyphosphate toxicity. High dietary phosphate from all sources is associated with elevated cardiovascular and renal risk, particularly in people with chronic kidney disease.
Polyphosphates are approved in the EU, US (GRAS), UK, Australia, and globally. They are pervasive in processed seafood, scallops, imitation crab, processed deli meats, and processed cheese spreads. Consumers monitoring phosphate intake — especially those with chronic kidney disease — should be aware that polyphosphate-containing processed foods can contribute significantly to daily phosphate load. Choosing minimally processed whole foods naturally reduces exposure to all added phosphates.
Generated from verified JECFA, EFSA, and regulatory data. All numerical values are sourced from the WHO/FAO JECFA Combined Compendium and EFSA OpenFoodTox 3.0.
Safety Assessment
| Body | Acceptable Daily Intake (ADI) | Year |
|---|---|---|
| JECFA | 0–70 mg/kg body weight/day (as phosphorus (group ADI with all phosphates)) · JECFA 1982(Expressed as as phosphorus (group ADI with all phosphates).) | 1982 |
| EFSA | — | — |
ADI = the amount of a substance a person can consume every day over a lifetime without appreciable health risk. Expressed as mg per kg body weight per day. Source: WHO/FAO JECFA Combined Compendium; EFSA OpenFoodTox 3.0.
Scientific Notes
Sequestrants used in processed meats and cheese to retain moisture. High cumulative phosphate intake linked to cardiovascular and renal burden.