All additives
E469·thickener

Enzymatically hydrolysed carboxymethylcellulose

Safe

Overview

Enzymatically hydrolysed carboxymethylcellulose is produced by treating sodium CMC (E466) with specific cellulase enzymes that cleave the cellulose backbone into shorter chain fragments. This hydrolysis reduces the molecular weight and therefore the viscosity of the resulting CMC, creating a low-viscosity stabiliser and thickener that can be incorporated into food systems where high viscosity would be undesirable. Its reduced chain length compared with standard CMC also affects its textural and stabilising properties, making it suited for specific applications such as beverage stabilisation and spray-dried encapsulation.

No JECFA numerical ADI has been established for enzymatically hydrolysed CMC. The modification is a physical/enzymatic process that does not introduce novel chemical structures — the resulting product is simply shorter-chain CMC. Its safety profile is anchored to the well-evaluated parent compound (E466), and no specific toxicological concerns have been identified for the hydrolysed form.

Enzymatically hydrolysed carboxymethylcellulose is approved in the EU as E469 for use as a food stabiliser and thickener in specific food applications. Its lower viscosity profile compared with high-molecular-weight CMC makes it particularly useful in spray-drying processes, fine emulsions, and applications where a lighter texture is required. It may appear alongside or instead of standard CMC (E466) in product formulations depending on the specific viscosity and stability requirements. Consumers encountering E469 on ingredient labels will typically find it in beverages, dairy products, or specialty food products where texture stability at lower viscosity is the technical requirement. No adverse effects at permitted use levels have been identified.

Generated from verified JECFA, EFSA, and regulatory data. All numerical values are sourced from the WHO/FAO JECFA Combined Compendium and EFSA OpenFoodTox 3.0.

Safety Assessment

BodyAcceptable Daily Intake (ADI)Year
JECFANot specified — no concern at typical intakes
EFSA

ADI = the amount of a substance a person can consume every day over a lifetime without appreciable health risk. Expressed as mg per kg body weight per day. Source: WHO/FAO JECFA Combined Compendium; EFSA OpenFoodTox 3.0.

Scientific Notes

Low-viscosity CMC produced by enzymatic hydrolysis; used as a stabiliser and thickener in specific food applications.

Primary Sources